Eosinophilic oesophagitis (EoE – or EE, if you are in the US) is a recognised but rare side effect of oral immunotherapy (OIT).<\/p>\n\n\n\n
We now understand it as a spectrum of gut related OIT issues. The classic signs of oesophagitis are burning central chest pain, reflux of stomach contents up into throat\/mouth, vomiting. Sometimes food gets stuck half way down after swallowing, which is really uncomfortable. <\/p>\n\n\n\n
In young kids it may be tricky to pick up – they may just have reduced appetite and poor weight gain.<\/p>\n\n\n\n
It is seen in most kinds of oral immunotherapy, but some kids (and adults) get it without it being related to food allergy.<\/p>\n\n\n\n
To diagnose it requires endoscopy, which means a referral to a paediatric endocrinologist, and an anaesthetic. Raised eosinophils on a blood test can be a clue, but many allergic kids have this anyway. <\/p>\n\n\n\n
Many kids doing OIT get the odd sore stomach, or gas, or nausea, usually these symptoms settle quickly and you can keep going with OIT.<\/p>\n\n\n\n
If those symptoms become persistent and severe, you would be concerned about EoE – we would then reduce the dose but try to continue. <\/p>\n\n\n\n
We have never had to use any specific EoE treatment for any of our patients, but we can give omeprazole<\/strong>, which is often all you need.<\/p>\n\n\n\n You would only discontinue OIT if that wasn\u2019t working – once you have stopped OIT, things generally settle by themselves. If not, a gastroenterologist can give a course of budesonide<\/strong> after confirming the diagnosis. This seems to work very well.<\/p>\n\n\n\n So we think of it as a rare but manageable side effect, which in some unlucky cases might stop progress with OIT.<\/p>\n","protected":false},"excerpt":{"rendered":" Eosinophilic oesophagitis (EoE – or EE, if you are in the US) is a recognised but rare side effect of oral immunotherapy (OIT). We now understand it as a spectrum of gut related OIT issues. The classic signs of oesophagitis are burning central chest pain, reflux of stomach contents up into throat\/mouth, vomiting. Sometimes food […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-60","post","type-post","status-publish","format-standard","hentry","category-side-effects"],"_links":{"self":[{"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/posts\/60","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/comments?post=60"}],"version-history":[{"count":1,"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/posts\/60\/revisions"}],"predecessor-version":[{"id":61,"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/posts\/60\/revisions\/61"}],"wp:attachment":[{"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/media?parent=60"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/categories?post=60"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/food.peanutimmunotherapy.scot\/index.php\/wp-json\/wp\/v2\/tags?post=60"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}